Gastric cancer (GC) is one of the leading causes of cancer-related deaths worldwide.The major problems of patients with GC are the lack of proper response to the treatment, drug resistance and metastasis attributed to the presence of a subpopulation of cells inside the tumour that are called cancer stem cells (CSCs).In addition, deregulation of mic
K6PC-5 Activates SphK1-Nrf2 Signaling to Protect Neuronal Cells from Oxygen Glucose Deprivation/Re-Oxygenation
Background/Aims: New strategies are S2 GRAPE required to combat neuronal ischemia-reperfusion injuries.K6PC-5 is a novel sphingosine kinase 1 (SphK1) activator whose potential activity in neuronal cells has not yet been tested.Methods: Cell survival and necrosis were assessed with a Cell Counting Kit-8 assay and lactate dehydrogenase release assay,
Addition of Phosphatases and Phytases to Mature Compost to Increase Available Phosphorus: A Short Study
Agriculture depends on fertilizers to provide nutrients for plants.Phosphorus (P) is one of these nutrients and is the second-most necessary for plant growth.Global production of P fertilizer is concentrated in Morocco, China and the United States.A large amounts of P resources are found in organic wastes that can be transformed through phosphate-s
Neuroscience, Moral Psychology and Law: First Lines on the (Im)possibility of Rational Persuasion
Although Law is often influenced by values, nowadays a widely Suspension Shock Absorber Bracket held expert opinion is that the application of law is a result or rational reasoning.It is believed that those applying legal rules consider the conflicting arguments from both parties, and come to a decision by rational means.Nevertheless, new discoveri